A PhD student supported by National Rehabilitation Centre (NRC) funding has successfully completed his doctorate at Loughborough University and has helped to create a new research organisation using 3D muscle models.
Dr Pablo Marco Garrido recognised that whilst 2D lab grown tissue cultures have provided insights into myogenic differentiation, they fail to replicate the complex architecture and contractile behaviour of native muscle.
In contrast, 3D models better mimic in vivo conditions, promoting alignment, extracellular matrix integration, and functional maturation. However, the relationship between structural development and contractile performance in these models is not well understood.
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A neurorehabilitation Occupational Therapist based at Nottingham University Hospitals NHS Trust has successfully completed a research project into improving discharge for complex rehabilitation patients leaving the brand-new National Rehabilitation Centre.
The NRC, a 70-bed state-of-the-art specialist rehabilitation centre for NHS patients who have experienced a life-changing illness or injury, will be run and staffed by Nottingham University Hospitals NHS Trust (NUH) when it opens in early 2026.
Anna Marshall, who works in the Reablement Team at City Hospital, received funding from the NHS England Midlands Fellowship Programme to carry out the research.
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